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Research indicates that while the disease burden of COPD on the Chinese population has shown a general downward trend in recent years, it still remains at a relatively high level 5

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However, ongoing efforts to eliminate the disease have failed and syphilis remains a public health problem in both developed and developing countries worldwide

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In these bacteria, the assembly of HrpE into the pilus is essential for the secretion of different transcription activator-like (TAL) effectors, which play key roles in Xanthomonas -host interactions 6